Arsenal boss Mikel Arteta has urged the Premier League to protect clubs against "very difficult" turnarounds between games.
Arteta's side
lost 3-1 to title rivals Emirates Marketing Project in the Premier League on Wednesday evening..
The Gunners will be back in league action only 63 hours after the defeat when they take on Aston Villa in Saturday's 12:30 GMT slot.
"There are certain rules with the Champions League," Arteta said.
"When you are playing on Wednesday night and then you cannot play [on Saturday lunchtime]. So I think that should apply to any competition."
In 2020, Liverpool manager Jurgen Klopp
criticised broadcasters for placing a Premier League game on a Saturday lunchtime after a Champions League game on Wednesday.
The rules were changed in 2021 to prevent Champions League clubs from playing in the Premier League's early Saturday slot if they had played an away game in Europe on the Wednesday.
"Following the same principle, I think you are talking physiologically, that is very difficult to turn around on that period to get the best outcome and reduce the injury risk for players," Arteta said before Saturday's game at Villa Park.
"They put the schedule the way they did. It's a bit unusual, but it's what it is.
"It's not about being worried or not worried. We have to play. I want the players to be in the best possible mindset and physically ready to get that challenge going."