We can rotate because we have a good squad of players. It'd be pretty easy to think of lineups right up to Arsenal at home, injuries permitting, a know-nothing like me can do it. Mostly it'd be 3 or 4 changes, bar the cup game against Palace where we could risk a few more:
Sun - PL - City (a):
-------------lloris
walker----toby----wimmer----rose
----------dier-----dembele
--son---------alli--------eriksen
-------------kane
Thur- EL - Fiorentina (a): 4 changes
-------------lloris
trippier----toby----wimmer----davies
----------dier-----dembele
--lamela---------eriksen--------chadli
-------------kane
Sun - FAC- Palace (h): 7 changes
-------------vorm
walker----dier----wimmer----rose
--------bentaleb-----mason
--lamela---------carroll--------chadli
-------------son
Thur- EL - Fiorentina (h): 8 changes
-------------lloris
trippier----toby----wimmer----davies
----------dier-----dembele
--son---------alli--------eriksen
-------------kane
Sun - PL - Swansea (h): 4 changes
-------------lloris
walker----toby----wimmer----rose
----------dier-----mason
--lamela---------eriksen--------son
-------------kane
Weds- PL - West Ham (a): 4 changes
-------------lloris
tripper----toby----wimmer----davies
----------dier-----dembele
--son---------alli--------eriksen
-------------kane
Sat - PL - Arsenal (h): 3 changes
-------------lloris
walker----toby----wimmer----rose
----------dier-----dembele
--lamela---------alli--------eriksen
-------------kane
Something like that, I'm sure Poch has lineups in mind for each game and he'll tweak them for injuries and form as necessary.