Without modern day financial doping:
Man U
Liverpool
Arsenal
Spurs
Everton
Aston Villa
- all clubs in the group above historically have had large, organically-generated domestic fan bases. Still strong today with broader int'l appeal.
Chelsea (before Abramovich they were Fulham with a bit more money but no taste or brains. With Boehly, same deal)
Emirates Marketing Project (The Maine Rd. Hillbillies until Jed Clampett struck oil. Feared but neither loved nor respected. Highly disposable item for plastic fans)
Saudi Sportswashing Machine (Huge locally, not so huge internationally)
West Ham (Millwall with a bit more money but no taste or brains)
Leeds (could be huge with proper ownership)
Nottingham Forest (yes, great Euro success at one time but not a huge club)
The. Rest.