For me, it's got to be:
.....................Lloris
...Walker...Daws..Vertonghen..Naughton
.............Sandro..Paulinho
..Lamela......Eriksen......Townsend
.................Soldado
Subs to include Dembele, Defoe, Siggy, Ade and Lennon
I've made no secret of my pretty negative views on Townsend, but I accept that he's in good form and confident and on that basis must start.
But Lamela needs to start getting into the action, and for me Townsend shifting to the left and Lamela on the right is the way to accommodate both. I would imagine Villa will expect Townsend to start on the right, so it'll do no harm to shift him to the other side - it also makes it less likely that ever other attack will end with him cutting inside onto his right before blasting wide!!
Sandro and Paulinho make (I think) a pretty devastating central pairing. I'd like to see them start together, even though that comes at the cost of Dembele being benched.
Soldado rather than Defoe for me - he's a class act and knows where the net is, he just needs to get a goal and it'll come good.
COYS.